Assessment of disintegrant efficacy with fractal dimensions from real-time MRI
نویسندگان
چکیده
منابع مشابه
Assessment of disintegrant efficacy with fractal dimensions from real-time MRI.
An efficient disintegrant is capable of breaking up a tablet in the smallest possible particles in the shortest time. Until now, comparative data on the efficacy of different disintegrants is based on dissolution studies or the disintegration time. Extending these approaches, this study introduces a method, which defines the evolution of fractal dimensions of tablets as surrogate parameter for ...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2014
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2014.09.021